GlidedosePrices checked October 24, 2026. All amounts in US dollars.
Ozempic vs Wegovy vs Zepbound: what each costs in the US
This is a price comparison only. It does not compare how well the medications work or which one you should take; that's a conversation with your prescriber.
Price by dose (October 2026)
| Medication (maker) | Form | Self-pay price per month | List price per month |
|---|---|---|---|
| Ozempic (Novo Nordisk) | weekly pen | $199 for 0.25 and 0.5 mg (first two fills for new patients, through Dec 31, 2026), then $349 for 0.25–1 mg; $499 for 2 mg | $1,027.51 |
| Wegovy (Novo Nordisk) | weekly pen | $199 for 0.25 and 0.5 mg (first two fills for new patients, through Dec 31, 2026), then $349 for 0.25–2.4 mg; $399 for 7.2 mg | $1,349.02 |
| Wegovy pill (Novo Nordisk) | daily tablet | $149 (1.5 mg), $199 (4 mg), $299 (9 and 25 mg) | — |
| Zepbound (Eli Lilly) | weekly, via LillyDirect | $299 (2.5 mg), $399 (5 mg), $449 (7.5–15 mg) if refilled within 45 days; otherwise $499 (7.5 mg) or $699 (10–15 mg) | about $1,087 |
| Mounjaro (Eli Lilly) | weekly pen | $499, all doses | $1,112.16 |
Self-pay prices from NovoCare and LillyDirect, list prices from GLP1Numbers' October 10, 2026 table. All prices in US dollars, with a valid prescription.
What the table means
- List price is the manufacturer's sticker price before insurance. People on high-deductible plans may pay close to it.
- Self-pay price is what the manufacturer charges cash-paying patients through NovoCare or LillyDirect (also shown on TrumpRx.gov).
- Novo Nordisk has announced lower list prices for Ozempic and Wegovy from January 1, 2027.
Frequently asked questions
Which is cheapest: Ozempic, Wegovy or Zepbound?
It depends on dose. At the starting doses, Ozempic and Wegovy pens are $199 for the first two fills for new patients, and Zepbound 2.5 mg is $299. At common maintenance doses, Wegovy is $349 (up to 2.4 mg), Ozempic $349 (1 mg) or $499 (2 mg), and Zepbound $449 with on-time refills.
Are Ozempic and Wegovy the same drug?
Both contain semaglutide and are made by Novo Nordisk, but they are approved for different uses and come in different doses. Which one, if any, is right for you is a decision for your prescriber.
Are Zepbound and Mounjaro the same drug?
Both contain tirzepatide and are made by Eli Lilly, with different approved uses. Self-pay prices differ: Mounjaro is $499 for all doses.
Sources
- NovoCare Pharmacy pricing (Novo Nordisk)
- Ozempic savings and self-pay offer (Novo Nordisk)
- Zepbound on LillyDirect (Eli Lilly)
- TrumpRx.gov
- NBC: Novo Nordisk list-price cuts from January 1, 2027
- GLP1Numbers self-pay and list-price table (October 10, 2026)
This page is general cost information, not medical, insurance or financial advice. Prices and program terms change often and eligibility rules apply. Confirm the current price with the manufacturer or your pharmacy, and talk to your prescriber about which medication and dose are right for you.